Abstract Discovery of new treatments for lymphoma that prolong survival and are less toxic than currently available agents represents an urgent unmet need.We now have a better understanding of the molecular pathogenesis of lymphoma, such as aberrant signal transduction pathways, which have led to the discovery and development of targeted therapeuti
Abstract Background Small cell lung cancer (SCLC) is an aggressive neuroendocrine cancer with an appalling overall survival of less than 5% (Zimmerman et al.J Thor Oncol 14:768-83, 2019).Patients typically respond to front line platinum-based doublet chemotherapy, but almost universally relapse with drug resistant disease.Elevated MYC expression is
Abstract Background Pentatricopeptide-repeat proteins (PPRs) are characterized by tandem arrays of a degenerate 35-amino-acid (PPR motifs), which can bind RNA strands and participate in post-transcription.PPR proteins family is one of the largest families in land plants and play important roles in organelle RNA metabolism and plant development.Howe
Survival time, percentage mortality, and feeding behavior were evaluated for adults of the weevil Myllocerus undecimpustulatus undatus Marshall (Coleoptera: Curculionidae) exposed to biopesticides by using a Petri dish plant-based bioassay system.Treatments consisted of Vanity three registered entomopathogenic fungal formulations (BotaniGard ES, PF